Best Document Control Software in the USA
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Compare the Top Document Control Software in the USA as of October 2026
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What is Document Control Software in the USA?
Document control software is designed to manage and track documents throughout their lifecycle, ensuring that they are properly stored, organized, and accessible. It provides features like version control, audit trails, and access permissions to maintain document integrity and security. This software helps organizations maintain compliance with industry standards and regulations by ensuring documents are updated and reviewed in a controlled manner. It also facilitates the efficient sharing and retrieval of documents, reducing the risk of errors or outdated information being used. By centralizing document management, document control software streamlines workflows and improves collaboration while minimizing risks associated with document mismanagement. Compare and read user reviews of the best Document Control software in the USA currently available using the table below. This list is updated regularly.
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1
isoTracker Quality Management
isoTracker Solutions Ltd
isoTracker Quality Management is a popular cloud-based quality management software (QMS) that is used by small to medium sized businesses on a worldwide basis. It helps to manage ISO 9001, ISO 13485, ISO 22000, ISO/IEC 17025, ISO 14001, ISO 45001, ISO/TS 16949, ISO 14971 systems...plus many other systems. It also conforms to the requirements of 21 CFR Part 11 and has been validated to it. It is a flexible and modular product with modules in document control, audit management, non-conformance management, customer complaints management, risk management, training management and CAPA management. It can be configured to meet an organization's specific needs and provides free training and free support. It has been independently judged to provide the best customer support in its category.Starting Price: $17 USD/month/user -
2
SBS Quality Management Software
Sunday Business Systems
The SBS Training Database is a comprehensive Learning Management System (LMS) that helps organizations plan, assign, deliver, track, and document employee training and competency. Manage instructor-led, self-paced, online, and on-the-job training from a centralized database. Automatically assign courses by job title, department, skill, or qualification, and send notifications for required, upcoming, overdue, and recurring training. Track attendance, quizzes, competency evaluations, certifications, electronic acknowledgments, and complete training histories with full audit trails. Store procedures, work instructions, videos, and other training documents with each course. Dashboards and reports identify training gaps, employee qualifications, certification status, and compliance metrics. The SBS Training Database helps organizations meet the training and competency requirements of ISO 9001, AS9100, ISO 13485, IATF 16949, FDA, OSHA, and other regulatory standards while improving workforceStarting Price: $4,268 one time fee -
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Interfacing Integrated Management System (IMS)
Interfacing Technologies Corporation
Interfacing provides controlled document lifecycle management for policies, SOPs, procedures, work instructions and other regulated content. Capabilities include authoring, review, endorsement, approval, publishing, electronic signatures, version history, scheduled periodic reviews, change requests, training assignments, read confirmations and archiving. Documents can be linked to processes, regulations, risks and roles, giving organizations visibility into downstream impacts when controlled content changes.Starting Price: $10/month/user -
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LogicalDOC
LogicalDOC
LogicalDOC helps organizations around the world gain complete control over document management. Focusing on business process automation and fast content retrieval, this premier document management system (DMS) allows teams to create, collaborate, and manage large volumes of documents and stores valuable company data in a centralized repository. System features include a drag-and-drop document upload, forms management, optical character recognition (OCR), duplicate detection, barcode recognition, event logging, document archiving, integrated document workflow, and so much more. Schedule a free, no obligation, one-on-one demo today. -
5
Intellect
Intellect
Intellect QMS is the latest version of Intellect's flagship product designed to help organizations and quality leaders meet FDA, ISO, and other global GxP regulatory compliance requirements. Intellect offers faster implementation time, robust out-of-the-box QMS capabilities, and extreme configurability to modify or build new apps. Empower your onsite and remote workforce with virtual auditing, online approvals, 21 CFR Part 11 electronic signatures, and ensure your team can access only approved and up-to-date quality documents, data, reports and analytics anytime, on any device. Intellect’s Environmental, health, safety and quality (EHSQ) software acts as a data management system for capturing, storing, and analyzing information related to occupational health and safety, waste management, and sustainability. It aims at reducing operational risk and improving health while attaining sustainability goals. -
6
Artintech ERP
Artintech
Artintech ERP is a comprehensive enterprise resource planning solution designed to optimize and streamline your business operations across various departments. Tailored for small to medium-sized enterprises (SMEs), Artintech ERP offers robust functionality with a user-friendly interface, allowing businesses to seamlessly manage their resources, inventory, human capital, finances, and customer relations all in one integrated platform. Artintech ERP includes a wide range of modules designed to optimize business operations. Key modules include Procurement, Warehousing, CRM, Distribution, Quality Management (QMS), Workplace Safety, Document Control, Non-Conformance and Corrective and Preventive Actions (CAPA), Inspection, and Computerized Maintenance Management System (CMMS).Starting Price: $24.95/Module/Month -
7
Q.Shop
QDataHub
Q.Shop, formerly known as Quince Shop Floor Data Collector, is a manufacturing software solution that is specifically designed for those in the repair and overhaul industry. Repair and overhaul manufacturing can be labour intensive and complex. Q.Shop is a unified data collection system that brings together shop floor inspection plans, process manuals, work instructions, and machinery inputs in one place. Q.Shop platform facilitates traceability and simplifies collaboration among technicians, supervisors, and managers. Q.Shop manufacturing solution also offers a complete job and employee scheduler. It maximizes process efficiency, in regard to not only machine operation but also personnel placement. Operators are scheduled based on their shift hours, experiences, skill levels and amount of achieved certifications/ licenses. Q.Shop increases productivity by providing the most suitable schedule for your current workforce, machinery, inventory and sales volume. -
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Total Lean Management (TLM) Software
Lean & Mean Business Systems
Perfect for a small company, TLM has everything you need, and can accelerate the implementation with consulting, training, procedure templates, and document writing/coaching support, plus we have validation templates and a system setting mode so small medical device companies have special features to help manage technical files and 510K submittals. TLM QMS Software saves you money AND makes your QMS more effective by providing a dual technology landscape for the two distinct QMS user types. Core modules include: • Audits • Contact Manager (CRM) • CAPA • Customer Feedback • Document Management • Electronic Forms • Employees • Employee Feedback • Equipment Calibration • Evaluations • FMEA • Inspections • Inventory/parts • Library • Meetings/Reviews • Metrics • Projects • Purchase Orders • Quality Record Mgt • Rejected Materials • Risk & Opportunities • Sales Orders • Strategic Planning • Surveys • Tasks/Events • Training • Work OrdersStarting Price: $45/user/month -
9
PinPoint Document Management System
LSSP Corporation
PinPoint DMS allows you and your staff to access files and data from anywhere in the world. Running on all platforms including MAC and mobile devices, PinPoint includes built-in tools for Workflow Management, Records Management, Onboarding, Publishing, Versioning, and full Content Search. The system can also automatically file documents without any human intervention. For over 19 years, PinPoint DMS has been enhancing our features that our competitors are just beginning to add. Find out how our document management software can help your organization go completely paperless!Starting Price: Ranges from $1 to $20 a month per user -
10
Adaptive Compliance Engine (ACE)
PSC Software
ACE is a quality management software solution for companies of any size, in any stage, in any highly regulated industry. ACE is fully configurable allowing your company to adapt ACE to fit into your exact quality needs. Empower all levels of your organization with intuitive user interfaces, easily search for all your documents and records, and transform your data into actionable intelligence with advanced analytics all on a single platform. Our one-stop software includes: -Office 365 Integration -Inspection Management -Document Management -Risk Management -Product Lifecycle Management -Learning Management -Audit Management -Quality Events -Paperless Validation -Electronic Signatures (21 CFR Part 11 Compliant) -Endless Workflow Configurations -And so much more! ACE comes with everything you need, all included at one price. Every application is included, no more a la carte pricing. No more nickel and diming. One software, endless solutions. -
11
Zapendo
Zapendo
Zapendo provides enterprise-level features for Contract Management and eSignature as a self-service platform that any company can afford. Small, medium and large businesses are all dealing with contracts. Zapendo will make sure you find your contracts with ease, know when they expire, and who the key stakeholders are. Custom workflows can enable you to establish your approval process for each contract, task, deliverable, or company that you create in Zapendo. eSignature features are included with each plan and are unlimited. All signed documents can be attached to one or multiple contracts.Starting Price: $12 per month -
12
MasterControl
MasterControl
Bringing breakthrough products to market in highly regulated industries can feel like an endless series of trade-offs. MasterControl's software simplifies GxP workflows so you never have to sacrifice quality for cost or innovation for regulation. Complete and connected meets fast and flexible. From quality event management to document control and integrated training - MasterControl Quality Excellence transforms your quality data and processes into a competitive advantage. Modernizing your manufacturing operations starts with modern software. From work orders to work instructions and production records (EBR or eDHR) to logbooks, MasterControl Manufacturing Excellence is the simplest way to digitalize manufacturing.Starting Price: $25,000 / 1st year -
13
Assai
Assai Software Services
Assai's DMS stores all your documents, drawings, correspondence, emails, contracts, and purchase orders in a central, easily searchable repository. You control access, and always have the latest versions available to your team. Search functions let you quickly find what you need using metadata or content. Our Document Control system streamlines workflows, with easy setup and maintenance, user inboxes, automatic assignments, and flowchart tracking. We offer Enterprise Content Management that enable complex projects and operations. Get a grip on your projects, assets, documents and data with our Common Data Environment.Starting Price: $5999/month -
14
AcceleratorKMS (Procedure Accelerator)
Innovatia Accelerator Inc.
With AcceleratorKMS organizations can eliminate information-caused incidents. Equip workers with mobile-ready content. Review and evergreen information. Streamline authoring and save costs. Monitor work and find efficiencies. Decrease time and money spent during onboarding. The Accelerator provides an integrated digital content ecosystem in an easy-to-use and intuitive package focused on making the complex simple. Our goal is to make information easier to find for front-line workers, making operations safer. Reduce the chance of human error by giving workers instant access to digital Standard Operating Procedures (SOP), policies, and training content on a mobile device. Reduce the chance of information-caused incidents through standardizing all operational content, and make it easier to use with AI-assisted procedure authoring. Reduce administrative involvement and management effort as standardization reduces the overall amount of operational content. -
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QT9 QMS
QT9 Software
Struggling with complex compliance requirements or disconnected quality systems? QT9 QMS eliminates these challenges with one integrated, fully validated platform that scales with your business. Designed for life sciences, aerospace, and manufacturing, QT9 offers cloud or secure on-premise deployment to meet your needs. Stay audit-ready automatically with built-in FDA, ISO, and EU MDR compliance while reducing manual work by up to 70%. With 28+ modules included—like document control, CAPA, training, and supplier management—QT9 deploys fast without costly customization. Backed by ISO 27001 certification, unlimited support, and 20+ years of proven success, QT9 helps 1,100+ organizations accelerate compliance, improve visibility, and simplify quality management. Start your free trial or book a personalized demo today.Starting Price: $10,000/year -
16
FlinkISO
Techmentis Global Services
FlinkISO Quality Management System is one of the best quality management softwares available for small and medium business. Integrated with ONLYOFFICE editors, FlinkISO QMS allows you to build Custom HTML forms as per your QMS document's requirement. You can build your own QMS without any expert help or coding. To start with, modules like Audit Management, Customer Complaints, Document Management, Change Control etc are already in-built in the application. You can add your custom business rules, email triggers and even additional HTML fields with drag-and-drop feature. Application is available, both on-premise & on-cloud with flexible and affordable payment options. While on-cloud, you get 45+ days of evaluation period without making any payments, on-premise edition is available at USD80/mo.Starting Price: $80.00/month -
17
Dot Compliance QMS
QMS for Life Sciences
Dot Compliance provides the industry’s first off-the-shelf QMS solution – ready to deploy from day one, with little to no setup required, while also incorporating industry best practices and standards that address the latest global regulatory requirements. Powered by the Salesforce.com platform, our solutions enable life science organizations to quickly digitize their quality and compliance processes including Document Management, Training Management, Change Control, CAPA, Customer Complaints. Compliant with 21 CFR part 11, EU-Annex 11 and support ISO 9001, 13485, 14971, 27001 & MORE! Processes included: ▶ Document Management ▶ Training Management ▶ Quality Event Management ▶ CAPA Management ▶ Change Management ▶ Complaint Management ▶ Audit Management ▶ Supplier Quality Management ▶ Risk Management ▶ Design Control ▶ Deviations/Non-conformances ✔ Seamless Install ✔ Cost Effective ✔ One-Stop-ShopStarting Price: $10,000 / Annually -
18
Tricent
Tricent
Tricent is the #1 file-sharing governance SaaS platform that helps organizations make their file-sharing more secure and compliant without sacrificing collaboration. For Microsoft 365 OneDrive & Sharepoint, and Google Workspace MyDrives and Shared Drives. Tricent enables administrators to: 🚀 Effortless Onboarding in less than 30 Minutes. 🔍 Unparalleled Insights: From day one, gain a comprehensive overview of all files shared and permissions granted—across both personal drives and shared drives. ⭕️ Bulk Remediation Made Simple: Our admin-friendly cleanup tools allow you to tackle file sprawl efficiently. 😇 Empowering End-Users Responsibly: We use automation to involve your employees in the cleanup process. . 💪🏼 Customizable Governance Policies: Set different cycles for different user groups 🔮 Stay Ahead with Abnormality Detection: Our machine learning feature keeps you informed, detecting anomalies before they escalate *Only Google WorkspaceStarting Price: €18/year/user -
19
Elyse
Silkwood Software
Elyse® is a high-integrity controlled document management system that understands your data. Designed from the ground up to serve the people who use it, Elyse has a User-Centric data architecture that carefully mirrors the real world experience of how users expect controlled document management systems to behave. The result is: Users find what they need faster and experience less frustration. Administrators spend less time maintaining the system because there are fewer workarounds and customizations. Auditors have stronger evidence because foundational rules are hard wired. Organizations have a platform that is easier to validate and extend because it doesn't need program code to compensate for highly abstracted data. The product is configured and ready to use out of the box. Setting up Elyse does not require a team of specialists. For multi-user production environment deployment the license is a low friction trust-based per-database instance perpetual license.Starting Price: $3,500 -
20
Doc.It by IRIS
Doc.It Inc.
Document Management, Workflow, PDF Editing and Web Portal solutions for accounting firms to improve productivity and efficiency. Accounting and tax firms using Doc.It Suite software stay organized by streamlining and automating digital processes that drive efficiency, workflows and profitability while minimizing risk associated with dealing with the exchange and storage of financial documents. Doc.It was founded in 2001, is headquartered in Toronto, Canada and currently has 600 accounting firms and 16,000 users. There are three product options depending on your firms needs. 1. Doc.It Suite includes all functions of the software- Scan and Organize, document management, workflow, web portal, PDF Editor and all integrations. 2.. Doc.It Connect is focused around the web portal functionalities with the work binders for document storage. 3. Doc.It Explore is the starting point for document storage. and includes the PDF editorStarting Price: $29.00/month/user -
21
Legito
Legito
Document Automation & Contract Assembly; Smart Workflows, Approvals, & Document Management; Advanced Electronic Signature. All under one roof with Legito, your Smart Document Workspace. In under two hours, out-of-the-box functionality has you ready to automate documents that almost draft themselves. Over 140,000 users in 50 countries from top tier law firms and companies use Legito to manage documents, including LexisNexis, Price Waterhouse Coopers, Skoda Auto, and Societe Generale Group.Starting Price: $55 per user per month -
22
Xpublisher
Fabasoft Xpublisher
Fabasoft Xpublisher is one of the leading providers of editorial and publishing systems in the German-speaking area and part of Fabasphere—Fabasoft’s intelligent, cloud-native ecosystem. With Xpublisher, book and magazine publishers, media companies, as well as public research institutions, institutes, and associations create, manage, and publish their content: from planning and creating structured, media-neutral content, through managing editorial coordination processes, to automated print production and efficient distribution across all digital channels—all in compliance with the highest European data protection standards. The system is supported by the artificial intelligence of partner company Mindbreeze: The AI generates teasers, translations, and texts of the highest editorial quality and improves content reusability through automated tagging. -
23
Stendard Solution
Stendard
We are a regulatory consultancy and technology company that helps businesses implement international standards, streamline business processes across the organization, and accelerate global growth. Our team of in-house ISO consultants can provide trusted guidance towards your management systems requirements. Given our international expertise, besides experience with companies handling hardware and software products in nature, our advisory services have proven successful for a wide variety of clients. From setting up your QMS with a complete set of documents to maintaining your QMS through proper document version control and automated workflow processes, you will find valuable features tailored to your organization, regardless of whether you are a start-up or an established organization.Starting Price: $250 per month -
24
Document Locator
ColumbiaSoft
Document Locator is Windows-integrated document management software with available Web and Mobile access. It combines ease of use with enterprise-class capabilities. Fully-integrated into Microsoft Windows, Office, Outlook, and other business applications, Document Locator offers version control, notifications, approvals, security, records policies, and workflow all within the familiar Windows folders experience. The system is ideal for HR filing, Accounting, Projects, Contracts, Quality. An advanced API is also available for integration with other systems.Starting Price: $260 user/year -
25
Qualtrax
Qualtrax
Qualtrax is a complete quality and compliance software system used to manage and control documentation, automate key business processes with customizable workflows, streamline training management, manage internal and external audits and ensure critical industry regulations are addressed in real-time. Qualtrax is an invaluable resource in heavily-regulated industries, where complying with standards including ISO 17025, 17020, 13485, and 9001, TNI, GFSI, FDA, and FQS is required. -
26
MediaLab Document Control
MediaLab
MediaLab’s Document Control is a powerful way to manage your laboratory’s policies, procedures, and documentation. Our twenty years of expertise in clinical laboratories have created a document control solution that guides you to full compliance with all laboratory standards, regulations, and best practices. Document Control provides an automated, centralized platform for all of your document approvals, workflows, edits, sign-offs, audits, and more—with flexibility and customization features to match your laboratory’s unique needs. MediaLab's Document Control supports: • Digital records and version control of all documents, • Standardization across all documents from all sites, • Electronic signatures that meet 21 CFR Part 11 standards, • Customized approval workflows and processes, • Robust searching to easily locate specific documents, and more! -
27
SCHEMA ST4
SCHEMA Group
The SCHEMA Group was established in Nuremberg in 1995 and is a medium-sized software manufacturer with more than 130 employees. The SCHEMA Group produces component content management and content delivery solutions for authoring departments creating product-related content. The SCHEMA ST4 component content management system is one of the most frequently used systems for the modularised creation of documentation, package inserts and marketing documentation. The system covers all areas of creation, versioning, variant control, translation, management and publication of product-related content – from authoring assistance during input to the finished layout for the printed catalog. A documentation portal based on Quanos InfoCube provides a central point of contact on the Internet where all technical documentation is available. Users can quickly and precisely find the right content in the entire information inventory with an easy-to-use search system. -
28
BlueKanGo
BlueKanGo
Digitize your processes. Security. Environment. Quality. Hygiene. Of Business. Centralize. Simplify. Automate. One tool to manage everything. For a sustainable performance of your organization. The performance and safety of an organization is based on automated processes. BlueKanGo is the digital EHSQ solution to manage them. Whether you are looking to address societal and environmental issues, minimize your risks, improve your operational excellence, rely on the solution approved by more than 3500 customers for more than 18 years. Digitize your Quality, EHS and more processes. Quality & audits management. Health and Safety of employees. Environment. CMMS & inspection. Certification, Standards. Corporate Social Responsibility (CSR). Regulatory Watch. Strategic Planning. 6 differences that are our key strength. With more than 18 years of existence, BlueKanGo is the SaaS platform that has no limits but your imagination. An innovative, scalable and all-inclusive solution -
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Xeditor
Fabasoft Xpublisher
Xeditor is a professional online XML editor for XML authoring based on state-of-the-art web standards. By enabling authors to work together on structured content from any location at any time, Xeditor helps companies put efficient workflows in place. What’s more, the web-based architecture means there’s no need for time-consuming local installations. Xeditor, the professional online XML authoring tool, gives users the tools they need to create and edit structured documents intuitively in XML format. With the help of XML, content can be created in a way that is media-independent, semantically marked up, automatically processed, and published with a high degree of efficiency. XML is the data format of the future. Xeditor offers its users both an intuitive visual and a technical writing experience. Authors of subject-specific content benefit from the intuitive user interface of the visual XML editor, including WYSIWYG functionality. -
30
ComplianceQuest
ComplianceQuest
Fastest growing Enterprise Quality, Health and Safety Management System (QHSE) natively built and run on the Salesforce platform. Unified QHSE solutions, which combine EQMS and EHS, help our customers of all sizes deliver quality products and services in the safest, most sustainable way by mitigating risk, problems, and inefficiencies while protecting customers, employees, suppliers and brand. Every organization – irrespective of its industry, geography or size – involves an interaction of activities and processes with the environment. These activities may have an adverse or favorable impact on the environment depending on the type of activity being carried out. Our Environment Management solution has been designed to minimize and mitigate these adverse impacts on environment, to such an extent that our already depleting biodiversity is protected, and nurture an ecosystem where all living organisms coexist sustainably.Starting Price: $30 per user per month
