Open Source Python AI Agents

MindsDB is an AI data solution that enables humans, AI, agents, and applications to query data in natural language and SQL, and get highly accurate answers across disparate data sources and types. MindsDB connects to diverse data sources and applications, and unifies petabyte-scale structured and unstructured data. Powered by an industry-first cognitive engine that can operate anywhere (on-prem, VPC, serverless), it empowers both humans and AI with highly informed decision-making capabilities. A federated query engine that tidies up your data-sprawl chaos while meticulously answering every single question you throw at it. MindsDB has an MCP server built in that enables your MCP applications to connect, unify and respond to questions over large-scale federated data—spanning databases, data warehouses, and SaaS applications.

Semantic Router is a superfast decision-making layer for your LLMs and agents. Rather than waiting for slow, unreliable LLM generations to make tool-use or safety decisions, we use the magic of semantic vector space — routing our requests using semantic meaning. Combining LLMs with deterministic rules means we can be confident that our AI systems behave as intended. Cramming agent tools into the limited context window is expensive, slow, and fundamentally limited. Semantic Router enables lightning-fast and cheap tool usage that can scale to many thousands of tools. LLMs are slow, yet we use them for every decision in agentic use-cases. Semantic Router swaps slow LLM calls for superfast route decisions.

autoresearch is an experimental framework that enables AI agents to autonomously conduct machine learning research by iteratively modifying and training models. Created by Andrej Karpathy, the project allows an agent to edit the model training code, run short experiments, evaluate results, and repeat the process without human intervention. Each experiment runs for a fixed five-minute training window, enabling rapid iteration and consistent comparison across architectural or hyperparameter changes. The system centers on a simple workflow where the agent modifies a single training file while human researchers guide the process through a program.md instruction file. Designed to run on a single GPU, it keeps the research loop minimal and self-contained to make autonomous experimentation practical. Over time, the agent logs experiments, evaluates improvements, and gradually evolves the model through automated trial-and-error.